Dicarboxylic acids and derivatives
Medchemexpress LLC Pigment Yellow 101 | 2387-03-3 | 98.06% | 50 MG
Pigment Yellow 101 is a yellow bis-azomethine pigment that exhibits solid-state fluorescence with excitation/emission at 411 nm/512 nm. This product is available as a commercial colorant.
- Yellow bis-azomethine pigment
- Excitation/emission: 411 nm/512 nm
- Exhibits solid-state fluorescence
- Available as a commercial colorant
Apexbio Technology LLC PKUMDL-LC-101-D04 2143896-83-5 10mg
PKUMDL-LC-101-D04 (CAS 2143896-83-5) is a small molecule allosteric activator of glutathione peroxidase 4 (GPX4) a key enzyme regulating ferroptosis In biochemical and cell extract assays PKUMDL-LC-101-D04 enhances GPX4 activity to 150% of baseline at concentrations of 20 M and 61 M respectively This compound serves as a valuable tool for investigating the modulation of ferroptosis through GPX4 activation and supports research into oxidative stress and cell death mechanisms
Medchemexpress LLC VNT-101 | 2894060-67-2 | 99.5% | 456.41 | 5 MG
VNT-101 is an orally active influenza A (IAV) inhibitor that disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex. It exhibits potent antiviral activity across multiple influenza A subtypes and robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. It can be used for the study of influenza A infection.
- Orally active influenza A (IAV) inhibitor.
- Disrupts NP-NP PPI to block NP oligomerization.
- Destabilizes the viral ribonucleoprotein (RNP) complex.
- Potent antiviral activity across multiple influenza A subtypes.
- Exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay.
- Demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus.
Medchemexpress LLC Rhodamine 101 chloride | 64339-18-0 | 527.05 g/mol | C32H31ClN2O3 | 10 MG
Rhodamine 101 chloride is a bright xanthene-class fluorescent dye with excitation and emission maxima at 565 nm and 595 nm, respectively. It is used for fluorescence microscopy, cellular staining, and as a red-spectrum reference standard. The solid is supplied in small laboratory pack sizes and should be stored protected from light and moisture; in solvent store at -80°C (up to 6 months) or -20°C (up to 1 month).
- Excitation 565 nm and emission 595 nm.
- Suitable for fluorescence microscopy and cellular staining.
- Useful as a reference standard in red-spectrum labeling.
- Available in small lab pack sizes, including 10 mg.
- Store sealed, protected from moisture and light.
Medchemexpress LLC PKUMDL-LC-101-D04 25mg | 2143896-83-5 | 378.9 | C14H22N4O2S2 • HCl | 25 MG
PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4). It increases GPX4 enzymatic activity (pEC50 = 4.7) in biochemical and cell-based assays and has been reported to inhibit ferroptosis and inflammatory responses. The compound is supplied as the monohydrochloride salt with reported high purity and is intended for research use.
Selleck Chemical LLC NLX-101 S3510-5mg
NLX-101 (F-15599) is a highly selective 5-HT1A receptor biased agonist that mediates antidepressant-like activity in rats via prefrontal cortex 5-HT 1A receptors
Medchemexpress LLC PKUMDL-LC-101-D04 50mg | 2143896-83-5 | 378.94 g·mol⁻¹ | C14H23ClN4O2S2 | 50 MG
Small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used as a research tool to study ferroptosis and inflammation. Reported activity includes an approximate pEC50 of 4.7 and an ability to increase GPX4 activity in biochemical assays. Supplied as a solid with good solubility in DMSO for assay preparation.
- Allosteric activation of glutathione peroxidase 4 with reported pEC50 ≈ 4.7.
- Shown to increase GPX4 activity to about 150% in biochemical assays.
- Useful for probing ferroptosis and inflammation pathways in preclinical research.
- Supplied as a solid with high DMSO solubility for convenient dilution and assay use.
- Vendor-reported molecular formula and molecular weight provided for analytical reference.
Medchemexpress LLC ULK-101 25mg | 2443816-45-1 | 460.45 | C22H16F4N4OS | 25 MG
ULK-101 is a potent, selective small-molecule inhibitor of ULK1 used in cellular and biochemical research to suppress autophagy and sensitize cancer cells to nutrient stress.
- Potent ULK1 inhibition (IC50 = 1.6 nM) with lower activity on ULK2 (IC50 = 30 nM).
- High purity suitable for research applications (99.91%).
- Available as a powder in multiple pack sizes, including 25 MG, and as DMSO solution formats.
- Storage-stable when kept at recommended temperatures for powder and solutions.
- Molecular weight 460.45 and molecular formula C22H16F4N4OS.
Medchemexpress LLC Uk-101 | 1000313-40-5 | 99.6% | 484.74 | C25H48N2O5Si | 10 MG
UK-101 is a potent, selective inhibitor of the immunoproteasome β1i (LMP2) subunit used as a biochemical probe to study immunoproteasome activity and apoptosis-related pathways.
- Potent LMP2 inhibition (IC50 ≈ 104 nM).
- High selectivity versus β1c and β5 subunits.
- High purity suitable for research use (≈99.6%).
- Soluble in DMSO (≈7.3 mg/mL); may require warming or sonication.
- Supplied in small quantities appropriate for laboratory assays.
- Commonly used in biochemical assays and apoptosis research.
Medchemexpress LLC 7-((4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 50 MG
CUDC-101 is a small-molecule research inhibitor of histone deacetylases (HDACs), epidermal growth factor receptor (EGFR), and HER2, used in preclinical cancer research to assess antiproliferative and target-specific effects.
- Potent inhibitor of HDAC, EGFR, and HER2 with low-nanomolar activity.
- Demonstrates broad antiproliferative effects across cancer cell lines.
- Supplied as a light yellow to yellow powder for laboratory use.
- High purity suitable for research applications (reported ≥98% by HPLC).
- Available in small-mass packaging for research workflows.
- Molecular weight 434.49 g/mol.
Medchemexpress LLC Rhodamine 101 hydrochloride | 64339-18-0 | 95.0% | 563.51 | 25 MG
Rhodamine 101 hydrochloride is a fluorescent dye. It is known for its bright fluorescence and specific excitation and emission characteristics.
- Exhibits bright fluorescence
- Excitation maxima at 565 nm
- Emission maxima at 595 nm.
Medchemexpress LLC Rhodamine 101 hydrochloride | 64339-18-0 | MFCD00210089 | >=95% | 563.51 | 5 MG
Rhodamine 101 chloride (Rhodamine 640 chloride) hydrochloride is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.
- For research use only.
- We do not sell to patients.
Apexbio Technology LLC Sulforhodamine 101 60311-02-6 25mg
Sulforhodamine 101 (60311-02-6) is a red-emitting fluorescent dye primarily utilized as a selective marker for astrocytes Sulforhodamine 101 selectively accumulates in astrocytes enabling differentiation from surrounding neuronal populations In neurobiological studies using live tissue imaging including acute brain slice preparations the dye facilitates visualization of astroglial cell morphology and cellular dynamics Based on these properties Sulforhodamine 101 holds research potential in the study of astrocyte-specific responses morphological characteristics and cell cell interactions within neuronal tissues
Medchemexpress LLC PKUMDL-LC-101-D04 500mg | 2143896-83-5 | 378.93 g·mol⁻¹ | C14H23ClN4O2S2 | 500 MG
PKUMDL-LC-101-D04 is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used in research on ferroptosis, lipid peroxidation, and inflammation. It increases GPX4 enzymatic activity in cell-free and cellular assays (reported pEC50 = 4.7) and protects cells from cholesterol peroxide-induced toxicity.
- Allosteric activator of GPX4, reported pEC50 = 4.7.
- Increases GPX4 activity to ~150% in cell-free and cellular extracts at reported concentrations.
- Demonstrated inhibition of ferroptosis and protection against lipid peroxide-induced cell death.
- Molecular weight ~378.93 g·mol⁻¹ and chemical formula C14H23ClN4O2S2.
- Supplied as a high-purity research chemical suitable for biochemical and cellular assays.